| Nipple-sparing mastectomy and immediate tissue expander/implant breast reconstruction. | |
| | |
MedLine Citation:
|
PMID: 19952633 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The nipple is an uncommon site for breast cancer development, but the nipple-areola complex is routinely excised in breast cancer treatment. The authors evaluated the risks and benefits of nipple- or areola-sparing mastectomy with breast reconstruction. METHODS: The authors analyzed data on 115 consecutive nipple- or areola-sparing mastectomies with immediate tissue expander breast reconstruction performed in 66 patients from 1998 to 2008 at a single tertiary-care cancer center. Nipple-sparing mastectomies were performed for prophylaxis (n = 75) or treatment of disease (n = 40). RESULTS: Mean patient age was 45 years (range, 24 to 61 years) and mean follow-up time was 22 months (range, 2 weeks to 91 months). There were 115 nipple- or areola-sparing mastectomies (48 bilateral and 19 unilateral), including 111 nipple-sparing and four areola-sparing mastectomies. On pathologic review, 20 breasts had ductal carcinoma in situ, 20 breasts had invasive cancer, 11 breasts had lobular carcinoma in situ, one breast had phyllodes tumor, one breast had mucinous carcinoma, and 62 breasts were cancer-free. Incision placement was periareolar and radial (n = 61), inframammary (n = 25), omega type (n = 14), customized to include a previous scar (n = 10), or transareolar (n = 5). Of all 115 nipple- or areola-sparing mastectomies, six nipples were lost because of occult disease (5.2 percent), and four nipples were lost because of wound-healing problems (3.5 percent). CONCLUSIONS: In the authors' series of nipple- and areola-sparing mastectomies performed for risk reduction or breast cancer, there was a low incidence of occult disease (5.2 percent). Nipple- and areola-sparing mastectomy may be feasible in selected patients and should be the subject of additional investigation. |
| | |
Authors:
|
Constance M Chen; Joseph J Disa; Virgilio Sacchini; Andrea L Pusic; Babak J Mehrara; Carlos A Garcia-Etienne; Peter G Cordeiro |
Related Documents
:
|
19331943 - Breast asymmetry. 21114613 - Relation between pain and skeletal metastasis in patients with prostate or breast cancer. 22609813 - The biology of human breast epithelial progenitors. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Plastic and reconstructive surgery Volume: 124 ISSN: 1529-4242 ISO Abbreviation: Plast. Reconstr. Surg. Publication Date: 2009 Dec |
Date Detail:
|
Created Date: 2009-12-02 Completed Date: 2010-01-11 Revised Date: 2011-02-16 |
Medline Journal Info:
|
Nlm Unique ID: 1306050 Medline TA: Plast Reconstr Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 1772-80 Citation Subset: AIM; IM |
Affiliation:
|
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Breast Implants Breast Neoplasms / pathology, surgery Cohort Studies Esthetics Female Follow-Up Studies Graft Rejection Graft Survival Humans Mammaplasty / methods* Mastectomy, Subcutaneous / methods* Middle Aged Neoplasm Invasiveness / pathology Neoplasm Recurrence, Local / epidemiology*, pathology Neoplasm Staging Nipples / pathology* Patient Satisfaction Patient Selection Postoperative Care / methods Retrospective Studies Risk Assessment Time Factors Tissue Expansion Devices* Treatment Outcome Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Three- and four-dimensional arterial and venous perforasomes of the internal mammary artery perforat...
Next Document: Preferences in choosing between breast reconstruction options: a survey of female plastic surgeons.