Document Detail

Nine months aerobic fitness induced changes on blood lipids and lipoproteins in untrained subjects versus controls.
MedLine Citation:
PMID:  17186304     Owner:  NLM     Status:  MEDLINE    
Regular endurance exercise has favorable effects on cardiovascular risk factors. However, the impact of an exercise-induced change in aerobic fitness on blood lipids is often inconsistent. The purpose of this study was to investigate the effect of nine consecutive months of training on aerobic fitness and blood lipids in untrained adults. Thirty subjects 35-55 years of age (wt: 73.1 +/- 13.6 kg, height 171.1 +/- 9.0 cm, %body fat 24.6 +/- 6.3%, 14 males and 16 females) were randomly assigned to an exercise (EG) (N = 20) and control (CG) (N = 10) group. All subjects completed an incremental treadmill test, anthropometric measurements, and venous blood sample collection before and after the 9 months of exercise. Participants in the exercise group were supervised and adjusted for improvements in running performance, whereas no change was administered for the control group. One-way and multivariate ANOVA was conducted to determine significant differences in means for time and group in selected variables [body mass, % body fat, BMI; VO(2peak), km/h at 2.0 (v-LA2) and 4.0 (v-LA4) mmol l(-1) blood lactate (LA) concentration, km/h of the last load (v-max); TC, LDL-C, HDL-C, TG, Apo B, Apo A-1, and Lp (a)]. Correlation coefficients and multivariate regression analysis was used to determine the association between aerobic fitness and blood lipids. The exercise group improved significantly (P < 0.0001) in VO(2peak), v-LA2, v-LA4, v-max and exhibited a significant decrease in Apo B (P < 0.04) compared to the control group (NS). In 9 months, E achieved 24% increase in VO(2peak) and 18% reduction in Apo B, denoting the impact of cardiovascular fitness on cardiovascular risk.
Susanne Ring-Dimitriou; Serge P von Duvillard; Bernhard Paulweber; Monika Stadlmann; Linda M Lemura; Kayla Peak; Erich Mueller
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2006-12-22
Journal Detail:
Title:  European journal of applied physiology     Volume:  99     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-26     Completed Date:  2007-04-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  291-9     Citation Subset:  IM    
Department of Sport Science and Kinesiology, University of Salzburg, Salzburg, Austria.
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MeSH Terms
Analysis of Variance
Apolipoprotein A-I / blood
Apolipoproteins B / blood
Cardiovascular Diseases / prevention & control
Cholesterol / blood
Exercise / physiology*
Linear Models
Lipids / blood*
Lipoprotein(a) / blood
Lipoproteins / blood*
Middle Aged
Oxygen Consumption
Reference Values
Time Factors
Triglycerides / blood
Reg. No./Substance:
0/Apolipoprotein A-I; 0/Apolipoproteins B; 0/Lipids; 0/Lipoprotein(a); 0/Lipoproteins; 0/Triglycerides; 57-88-5/Cholesterol

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