| Nifedipine therapy for Prinzmetal's angina. | |
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MedLine Citation:
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PMID: 411609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case is described in which nifedipine, a new coronary vasodilator, was effective in relieving attacks of Prinzmetal's angina unresponsive to conventional therapy. The extreme frequency of the anginal attacks provided evidence that lower doses of nifedipine lost their effectiveness approximately 4 hours after administration. A month after initiation of nifedipine, nitrates were withdrawn since they had been ineffective in controlling the attacks. A myocardial infarction occurred immediately, presumably due to coronary spasm. |
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Authors:
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J E Muller; S J Gunther |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Circulation Volume: 57 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1978 Jan |
Date Detail:
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Created Date: 1978-01-27 Completed Date: 1978-01-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 137-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angina Pectoris / drug therapy* Angina Pectoris, Variant / drug therapy* Coronary Disease / complications, etiology Humans Male Myocardial Infarction / etiology Nifedipine / therapeutic use* Nitroglycerin / therapeutic use Pyridines / therapeutic use* Substance Withdrawal Syndrome |
| Chemical | |
Reg. No./Substance:
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0/Pyridines; 21829-25-4/Nifedipine; 55-63-0/Nitroglycerin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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