Document Detail


Nifedipine for digitalis-induced arrhythmias.
MedLine Citation:
PMID:  7404089     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The calcium antagonist, nifedipine (Adalat; Bayer), has previously been thought by most workers to lack cardiac-anti-arrhythmic properties, thus differing from verapamil. We have found that nifedipine was successful in converting cardiac glycoside (K-strophanthoside)-induced ventricular tachycardia to sinus rhythm in 4 of 5 anaesthetized dogs when given intravenously. In this respect, therefore, nifedipine is similar to verapamil. Further work is advocated before applying these results to the clinical situation in man.
Authors:
F H Spracklen; L H Lazarus
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  57     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1980 Jun 
Date Detail:
Created Date:  1980-10-27     Completed Date:  1980-10-27     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  1046     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Arrhythmias, Cardiac / chemically induced,  drug therapy*
Dogs
Nifedipine / therapeutic use*
Phenytoin / therapeutic use
Pyridines / therapeutic use*
Strophanthins / pharmacology
Verapamil / therapeutic use
Chemical
Reg. No./Substance:
0/Pyridines; 0/Strophanthins; 6158TKW0C5/Phenytoin; CJ0O37KU29/Verapamil; I9ZF7L6G2L/Nifedipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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