| Nicotine replacement: effects of postcessation weight gain. | |
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MedLine Citation:
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PMID: 2925978 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study examined nicotine replacement effects on postcessation weight gain in smoking cessation clinic volunteers using objective indices of cigarette smoking, gum use, and body weight. After they achieved abstinence, subjects were randomly assigned to either active nicotine or placebo gum conditions for 10 weeks, during which smoking status was carefully monitored. Analyses revealed strong evidence for a gum effect on weight gain, with active gum users gaining a mean total of 3.8 lb compared with 7.8 lb for placebo gum users at the end of the 10-week trial. Evidence for a dose-response relation was found, suggesting that more gum use (greater than or equal to 6.5 pieces/day) resulted in greater weight suppression. Placebo gum subjects reported greater postcessation increases in eating and hunger compared with active gum subjects. The implications of the weight suppression effect of nicotine gum for smoking cessation treatments are discussed. |
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Authors:
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J Gross; M L Stitzer; J Maldonado |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of consulting and clinical psychology Volume: 57 ISSN: 0022-006X ISO Abbreviation: J Consult Clin Psychol Publication Date: 1989 Feb |
Date Detail:
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Created Date: 1989-05-10 Completed Date: 1989-05-10 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0136553 Medline TA: J Consult Clin Psychol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 87-92 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Behavior Therapy Chewing Gum* Combined Modality Therapy Female Humans Male Middle Aged Nicotine / administration & dosage* Smoking / therapy* Weight Gain / drug effects* |
| Grant Support | |
ID/Acronym/Agency:
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DA 03893/DA/NIDA NIH HHS; T32 DA 07209/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Chewing Gum; 54-11-5/Nicotine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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