Document Detail

Nicotine patch and self-help video for cigarette smoking cessation.
MedLine Citation:
PMID:  9256568     Owner:  NLM     Status:  MEDLINE    
A total of 424 smokers were randomized in a 2 x 2 factorial experiment. A pharmacologic factor contained 2 levels: transdermal nicotine path (TNP; 21 mg) and placebo. A self-help behavioral treatment factor contained 2 levels: video-enhanced self-help treatment manual and self-help treatment manual only. At 2 months, TNP produced a higher level of abstinence (36%) than placebo (20%), p < .001. No other comparison was significant. In secondary analyses, (at 2 months) and compliance with patch treatment regimen (at 2, 6, and 12 months) were associated with less relapse. Although nicotine replacement therapy has improved our ability to produce smoking cessation, the production of sustained, longer term abstinence remains an elusive goal.
J D Killen; S P Fortmann; L Davis; A Varady
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of consulting and clinical psychology     Volume:  65     ISSN:  0022-006X     ISO Abbreviation:  J Consult Clin Psychol     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-09-29     Completed Date:  1997-09-29     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0136553     Medline TA:  J Consult Clin Psychol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  663-72     Citation Subset:  IM    
Center for Research in Disease Prevention, Stanford University School of Medicine, Palo Alto, California 94304-1885, USA. Killen@SCRDP.Stanford.EDU
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MeSH Terms
Administration, Cutaneous
Chi-Square Distribution
Logistic Models
Manuals as Topic*
Middle Aged
Nicotine / therapeutic use*
Nicotinic Agonists / therapeutic use*
Proportional Hazards Models
Prospective Studies
Self Care / methods*
Smoking Cessation / methods*
Survival Analysis
Treatment Outcome
Video Recording*
Grant Support
Reg. No./Substance:
0/Nicotinic Agonists; 54-11-5/Nicotine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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