Document Detail


Nicotine may relieve symptoms of Parkinson's disease.
MedLine Citation:
PMID:  7862924     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two elderly patients with Parkinson's disease were treated with nicotine gum and patch. Reliable changes in symptomatology were noted, using a single-subject, placebo-control reversal design. Improvement was associated with active nicotine dosing and involved diminished tremor and disorganized thinking in one patient and diminished bradykinesia and increased energy in the other.
Authors:
K O Fagerström; O Pomerleau; B Giordani; F Stelson
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Publication Detail:
Type:  Case Reports; Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Psychopharmacology     Volume:  116     ISSN:  0033-3158     ISO Abbreviation:  Psychopharmacology (Berl.)     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1995-03-23     Completed Date:  1995-03-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7608025     Medline TA:  Psychopharmacology (Berl)     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  117-9     Citation Subset:  IM    
Affiliation:
Pharmacia Research Laboratories, Helsingborg, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Administration, Cutaneous
Aged
Chewing Gum
Confusion / drug therapy,  etiology
Female
Humans
Male
Middle Aged
Muscle Rigidity / drug therapy,  etiology
Nicotine / administration & dosage,  therapeutic use*
Parkinson Disease / drug therapy*,  physiopathology,  psychology
Sleep Disorders / drug therapy,  etiology
Tremor / drug therapy,  etiology
Chemical
Reg. No./Substance:
0/Chewing Gum; 54-11-5/Nicotine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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