| Next generation of non-mammalian blood-brain barrier models to study parasitic infections of the central nervous system. | |
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MedLine Citation:
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PMID: 21921682 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Transmigration of neuropathogens across the blood-brain barrier is a key step in the development of central nervous system infections, making it a prime target for drug development. The ability of neuropathogens to traverse the blood-brain barrier continues to inspire researchers to understand the specific strategies and molecular mechanisms that allow them to enter the brain. The availability of models of the blood-brain barrier that closely mimic the situation in vivo offers unprecedented opportunities for the development of novel therapeutics. |
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Authors:
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Ruqaiyyah Siddiqui; James Edwards-Smallbone; Robin Flynn; Naveed Khan |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-01 |
Journal Detail:
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Title: Virulence Volume: 2 ISSN: 2150-5608 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101531386 Medline TA: Virulence Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Biological and Biomedical Sciences; Aga Khan University; Karachi, Pakistan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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