Document Detail

Newly reported hypertension after military combat deployment in a large population-based study.
MedLine Citation:
PMID:  19752293     Owner:  NLM     Status:  MEDLINE    
High-stress situations, such as combat deployments, are a potential risk factor for hypertension. Although stress is postulated to increase blood pressure, the underlying role of stress on hypertension is not well established. We sought to determine the relations between combat deployment-induced stress and hypertension. The Millennium Cohort baseline questionnaire (2001-2003) was completed by 77,047 US active-duty and Reserve/National Guard members. Follow-up was completed by 55,021 responders approximately 3 years later (2004-2006). Multivariable logistic regression was used to estimate the 3-year risk of newly reported hypertension, adjusting for general and mental health, demographics, and occupational and behavioral characteristics. After applying exclusion criteria, our analyses included 36 061 service members. Subanalyses of deployers included 8829 participants. Newly reported hypertension was identified in 6.9% of the cohort between baseline and follow-up, many of whom had deployed on military operations in support of the conflicts in Iraq and Afghanistan. After adjusting, deployers who experienced no combat exposures were less likely to report hypertension than nondeployers (odds ratio: 0.77; 95% CI: 0.67 to 0.89). Among deployers, those reporting multiple combat exposures were 1.33 times more likely to report hypertension compared with noncombat deployers (95% CI: 1.07 to 1.65). Although military deployers, in general, had a lower incidence of hypertension than nondeployers, deployment with multiple stressful combat exposures appeared to be a unique risk factor for newly reported hypertension.
Nisara S Granado; Tyler C Smith; G Marie Swanson; Robin B Harris; Eyal Shahar; Besa Smith; Edward J Boyko; Timothy S Wells; Margaret A K Ryan;
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2009-09-14
Journal Detail:
Title:  Hypertension     Volume:  54     ISSN:  1524-4563     ISO Abbreviation:  Hypertension     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-22     Completed Date:  2009-11-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  United States    
Other Details:
Languages:  eng     Pagination:  966-73     Citation Subset:  IM    
Department of Defense Center for Deployment Health Research, Naval Health Research Center, San Diego, CA 92106-3521, USA.
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MeSH Terms
Age Distribution
California / epidemiology
Cohort Studies
Combat Disorders / diagnosis,  epidemiology*,  prevention & control
Confidence Intervals
Hypertension / diagnosis,  epidemiology*
Logistic Models
Military Personnel / psychology,  statistics & numerical data*
Multivariate Analysis
Reference Values
Risk Factors
Severity of Illness Index
Sex Distribution
Stress Disorders, Post-Traumatic / diagnosis,  epidemiology,  prevention & control
Stress, Psychological / epidemiology*
Time Factors
United States
Young Adult
Paul Amoroso / ; Gina Creaven / ; James Davies / ; Lacy Farnell / ; Gary Gackstetter / ; Gregory Gray / ; Gia Gumbs / ; Tomoko Hooper / ; Isabel Jacobson / ; Kelly Jones / ; Molly Kelton / ; Cynthia LeardMann / ; Travis Leleu / ; Jamie McGrew / ; James Riddle / ; Katherine Snell / ; Steven Speigle / ; Kari Welch / ; Martin White / ; James Whitmer / ; Charlene Wong /
Comment In:
Hypertension. 2009 Nov;54(5):956-7   [PMID:  19752291 ]

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