Document Detail


Newly identified repeat sequences, derived from human chromosome 21qter, are also localized in the subtelomeric region of particular chromosomes and 2q13, and are conserved in the chimpanzee genome.
MedLine Citation:
PMID:  10869549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Subtelomeric regions have been a target of structural and functional studies of human chromosomes. Markers having a defined structure are especially useful to such studies. Here, we report 93 bp tandem repeat sequences found in the subtelomeric region of human chromosome 21q. They were also detected in the telomeric region of several other chromosomes. Interestingly, the repeat was also found in the 2q13 region which is known to be a position of chromosomal fusion, a major difference between the human and chimpanzee karyotypes. To the best of our knowledge, this repetitive sequence is a new member of human subtelomeric interspersed repeats.
Authors:
H S Park; M Nogami; K Okumura; M Hattori; Y Sakaki; A Fujiyama
Related Documents :
17696299 - Y-chromosome short tandem repeat dys458.2 non-consensus alleles occur independently in ...
11607059 - Multiple origins of polyploids in the glycine tabacina complex inferred from chloroplas...
10904119 - A regulatory polymorphism of the monoamine oxidase-a gene may be associated with variab...
3019869 - Repeated dna sequences in the distal long arm of the human x chromosome.
7604849 - Characterization of an unbalanced de novo rearrangement by microsatellite polymorphism ...
1211669 - Retina-specific ldh isozyme in blueback herring, alosa aestivalis (mitchell), and alewi...
22934239 - Ac/ds-induced chromosomal rearrangements in rice genomes.
18677109 - Direct visualization of the endomitotic cell cycle in living megakaryocytes: differenti...
23276569 - Prenatal diagnosis of mosaic tetrasomy 18p.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  FEBS letters     Volume:  475     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-07-24     Completed Date:  2000-07-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  167-9     Citation Subset:  IM    
Affiliation:
RIKEN Genomic Sciences Center, c/o Kitasato University, Sagamihara, Kanagawa 228-8555, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 2*
Chromosomes, Human, Pair 21*
Genome
Genome, Human
Humans
Molecular Sequence Data
Pan troglodytes / genetics*
Tandem Repeat Sequences*
Telomere

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Reduced hepatic fatty acid oxidation in fasting PPARalpha null mice is due to impaired mitochondrial...
Next Document:  Identification of an optimal Ncx binding sequence required for transcriptional activation.