Document Detail

Newly identified repeat sequences, derived from human chromosome 21qter, are also localized in the subtelomeric region of particular chromosomes and 2q13, and are conserved in the chimpanzee genome.
MedLine Citation:
PMID:  10869549     Owner:  NLM     Status:  MEDLINE    
Subtelomeric regions have been a target of structural and functional studies of human chromosomes. Markers having a defined structure are especially useful to such studies. Here, we report 93 bp tandem repeat sequences found in the subtelomeric region of human chromosome 21q. They were also detected in the telomeric region of several other chromosomes. Interestingly, the repeat was also found in the 2q13 region which is known to be a position of chromosomal fusion, a major difference between the human and chimpanzee karyotypes. To the best of our knowledge, this repetitive sequence is a new member of human subtelomeric interspersed repeats.
H S Park; M Nogami; K Okumura; M Hattori; Y Sakaki; A Fujiyama
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  FEBS letters     Volume:  475     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-07-24     Completed Date:  2000-07-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  167-9     Citation Subset:  IM    
RIKEN Genomic Sciences Center, c/o Kitasato University, Sagamihara, Kanagawa 228-8555, Japan.
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MeSH Terms
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 2*
Chromosomes, Human, Pair 21*
Genome, Human
Molecular Sequence Data
Pan troglodytes / genetics*
Tandem Repeat Sequences*

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