Document Detail

Newly diagnosed adult-onset Still disease in pregnancy.
MedLine Citation:
PMID:  12738120     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Adult-onset Still disease is a rare febrile disorder that can present for the first time during pregnancy. It is a diagnosis of exclusion with nonspecific laboratory results. Good maternal and fetal outcomes can be expected after initial diagnosis and treatment. CASE: A 21-year-old (gravida 2, para 1) at 20 weeks' gestation presented with fever, malaise, arthralgias, and cough. She had an extensive evaluation that led to the diagnosis of adult-onset Still disease. She was treated with prednisone and had immediate improvement. She delivered a viable infant at 34 weeks after suspected intrauterine growth restriction and continued to have recurrent symptoms postpartum. The second woman, 38 years old and gravida 3, para 1, aborta 1, presented at 22 weeks' gestation with similar symptoms and also had a similar diagnostic evaluation. She was diagnosed with adult-onset Still disease and started on prednisone, with immediate improvement, delivering a viable infant at 41 weeks' gestation. CONCLUSION: Adult-onset Still disease in pregnancy can be confused with many other diseases, but its diagnosis, after exclusion of other infectious, malignant, and rheumatic conditions, can portend good maternal and fetal outcomes.
Vivien L Pan; Atsuko Z Haruyama; Cristiane Guberman; Rodanthi C Kitridou; Deborah A Wing
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  101     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-09     Completed Date:  2003-05-15     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1112-6     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
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MeSH Terms
Anti-Inflammatory Agents / therapeutic use
Prednisone / therapeutic use
Pregnancy Complications / diagnosis*,  drug therapy
Pregnancy Outcome
Pregnancy Trimester, Second
Still's Disease, Adult-Onset / diagnosis*,  drug therapy
Reg. No./Substance:
0/Anti-Inflammatory Agents; 53-03-2/Prednisone

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