Document Detail


Newer biomarkers in heart failure.
MedLine Citation:
PMID:  19631181     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pathophysiology of heart failure is complex, and the list of biomarkers representing distinct pathophysiologic pathways is growing rapidly. This article focuses on some promising newer biomarkers that have contributed to a better understanding of pathophysiologic mechanisms involved in heart failure but for which less data are currently available: osteoprotegerin, galectin-3, cystatin C, chromogranin A, and the adipokines adiponectin, leptin, and resistin. Despite the intriguing early information from these newer markers, none is ready for routine clinical use. Much additional study is needed to determine how these biomarkers will fit into diagnostic and treatment algorithms for patients who have heart failure.
Authors:
Sachin Gupta; Mark H Drazner; James A de Lemos
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Heart failure clinics     Volume:  5     ISSN:  1551-7136     ISO Abbreviation:  -     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-07-27     Completed Date:  2009-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231934     Medline TA:  Heart Fail Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  579-88     Citation Subset:  IM    
Affiliation:
The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
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MeSH Terms
Descriptor/Qualifier:
Adipokines / blood
Biological Markers / blood
Cystatin C / blood
Galectin 3 / blood
Heart Failure / blood*,  diagnosis*
Humans
Osteoprotegerin / blood
Chemical
Reg. No./Substance:
0/Adipokines; 0/Biological Markers; 0/Cystatin C; 0/Galectin 3; 0/Osteoprotegerin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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