Document Detail


Newer antifungal agents.
MedLine Citation:
PMID:  15080413     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Invasive fungal infections have evolved into significant causes of morbidity and mortality in premature infants, immunocompromised children, and patients receiving immunosuppressive agents. Since the discovery in 1955, amphotericin B has been the cornerstone of antifungal treatment. The past 10 years, however, have witnessed a major expansion in the antifungal armamentarium through the development of less toxic formulations of Amphotericin B, the introduction of improved triazoles, and the advent of the echinocandin lipopeptides. In this article we discuss the Lipid-based amphotericin B, Voriconazole (a new azole), and Caspofungin (an echinocandin).
Authors:
Walid Abuhammour; Eyassu Habte-Gaber
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  71     ISSN:  0019-5456     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-04-14     Completed Date:  2004-05-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  253-9     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Hurley Medical Center, Michigan State University-College of Human Medicine, Flint, Michigan 48503-5993, USA. wabuham1@hurleymc.com
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MeSH Terms
Descriptor/Qualifier:
Antifungal Agents / therapeutic use*
Azoles
Child
Echinocandins
Humans
Infant, Newborn
Mycoses / drug therapy*
Peptides / pharmacology,  therapeutic use
Peptides, Cyclic*
Polyenes
Chemical
Reg. No./Substance:
0/Antifungal Agents; 0/Azoles; 0/Echinocandins; 0/Peptides; 0/Peptides, Cyclic; 0/Polyenes; 0/caspofungin

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