Document Detail


Newborn screening and the obstetrician.
MedLine Citation:
PMID:  22996108     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Newborn screening is the largest genetic screening program in the United States with approximately four million newborns screened yearly. It has been available and in continuous development for more than 50 years. Each state manages, funds, and maintains its own individual program, which encompasses newborn screening as well as the diagnosis and coordination of care for affected infants and children. The ideal disorder for screening is one in which newborn intervention prevents later disabilities or death for infants who may appear normal at birth. There are 31 core conditions that are currently recommended for incorporation into state screening programs. To obtain a sample, several drops of blood are collected from the newborn's heel and applied to filter paper. Although testing for core disorders is fairly standardized, more extensive screening varies by state and the rigorous evaluation of new disorders for inclusion in state screening panels is ongoing. As genomic medicine becomes more accessible, screening newborns for chronic diseases that may affect their long-term health will need to be addressed as well as the use of the residual blood spots for research. Obstetric providers should, at some time during pregnancy, review the basic process of newborn screening with parents to prepare them for this testing in the neonatal period. This information can be reviewed as it best suits incorporation in an individual's practice; verbal discussion and the distribution of written materials with resources for further information are encouraged.
Authors:
Nancy C Rose; Siobhan M Dolan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  120     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-21     Completed Date:  2013-01-24     Revised Date:  2013-10-17    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  908-17     Citation Subset:  AIM; IM    
Affiliation:
Intermountain Healthcare, University of Utah School of Medicine, Intermountain Medical Center, Maternal Fetal Medicine, Salt Lake City, Utah 84157, USA. Nancy.rose@imail.org
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MeSH Terms
Descriptor/Qualifier:
Congenital Abnormalities / diagnosis*
Female
Genetic Diseases, Inborn / diagnosis*
Humans
Infant, Newborn
Infant, Newborn, Diseases / diagnosis*
Neonatal Screening* / ethics,  methods,  organization & administration
Obstetrics
Patient Education as Topic
Pregnancy
Prenatal Care
United States
Grant Support
ID/Acronym/Agency:
R01 HG006266/HG/NHGRI NIH HHS
Comments/Corrections

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