Document Detail

Newborn retinal hemorrhages: a systematic review.
MedLine Citation:
PMID:  23363882     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To systematically review the characteristics, prevalence, evolution, and obstetric associations of retinal hemorrhages (RH) in newborns.
METHODS: A systematic review, searching 10 databases (1970-2011), identified 45 studies, which underwent two independent reviews via the use of standardized critical appraisal. Studies meeting the following criteria were included: examination by an ophthalmologist, use indirect ophthalmoscopy, and first examination conducted within 96 hours of birth and before hospital discharge.
RESULTS: Thirteen studies were included, representing 1,777 infants. The studies revealed that 25.6% of newborns born via spontaneous vaginal deliveries had RH. In contrast, infants delivered by vacuum extraction had a 42.6% rate of RH (OR, 2.75; 95% CI, 1.32-5.70), and infants delivered by double-instrument deliveries (forceps and vacuum) had a 52% rate of RH (OR, 3.27; 95% CI, 1.68-6.36). The hemorrhages are commonly bilateral (59%), of varying severity, from "mild" (22%-56%) to "severe" (18%-37%), and predominantly intraretinal and in the posterior pole. The majority of RH (83%) resolved within 10 days; isolated cases persisted to 58 days.
CONCLUSIONS: Birth-related RH in infants occurs in one-quarter of normal deliveries and are far more common after instrumental deliveries. Commonly bilateral, they were predominantly intraretinal, posterior, resolved rapidly, and very rarely persisted beyond 6 weeks.
Patrick Watts; Sabine Maguire; Thomas Kwok; Bnar Talabani; Mala Mann; Jarmila Wiener; Zoe Lawson; Alison Kemp
Publication Detail:
Type:  Journal Article; Review     Date:  2013-01-28
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  17     ISSN:  1528-3933     ISO Abbreviation:  J AAPOS     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-02-18     Completed Date:  2013-06-14     Revised Date:  2013-08-15    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  70-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff, United Kingdom.
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MeSH Terms
Birth Injuries / epidemiology*
Databases, Factual
Delivery, Obstetric*
Infant, Newborn
Retinal Hemorrhage / epidemiology*
Risk Factors
Erratum In:
J AAPOS. 2013 Jun;17(3):341

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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