Document Detail

Newborn apnea caused by a neurofibroma at the craniocervical junction.
MedLine Citation:
PMID:  8180909     Owner:  NLM     Status:  MEDLINE    
The authors report, for the first time, the finding by magnetic resonance imaging of a neurofibroma at the craniocervical junction with upper cervical cord and lower brainstem compression causing complete apnea from birth. Subsequent subtotal resection of the neurofibroma resulted in the successful extubation of a previously ventilator-dependent patient. After a two month period of breathing spontaneously, the newborn developed an upper respiratory tract infection and was reintubated. The patient, unable to be weaned off of the respirator, was extubated and expired shortly thereafter, at the age of five months. The authors suggest that in newborns with unexplained apnea, MRI of the cranio-cervical junction is indicated. Certain patients may be discovered who have less compromised cervico-medullary function and are afflicted by less aggressive forms of neurofibromatosis type 1. These patients may benefit permanently from a surgical decompression.
D B Clarke; J P Farmer; J L Montes; G V Watters; G Rouleau
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques     Volume:  21     ISSN:  0317-1671     ISO Abbreviation:  Can J Neurol Sci     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-06-15     Completed Date:  1994-06-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0415227     Medline TA:  Can J Neurol Sci     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  64-6     Citation Subset:  IM    
Division of Neurosurgery, Montreal Children's Hospital, McGill University, Quebec, Canada.
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MeSH Terms
Apnea / etiology*,  physiopathology
Brain Neoplasms / complications*,  pathology,  surgery
Infant, Newborn
Magnetic Resonance Imaging
Neurofibroma / complications*,  pathology,  surgery
Spinal Cord Compression / etiology,  pathology,  surgery
Spinal Cord Neoplasms / complications*,  pathology,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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