Document Detail

Newborn Oxygen Saturation at Mild Altitude versus Sea Level: Implications for Neonatal Screening for Critical Congenital Heart Disease.
MedLine Citation:
PMID:  23298328     Owner:  NLM     Status:  Publisher    
AIM: To determine the normal SpO(2) in healthy term newborns at mild-altitude (MA, 780 meters) compared to sea level (SL), within the context of universal screening for critical congenital heart disease (CCHD) METHODS: we studied 199 (119 at MA and 80 at SL) consecutively born healthy newborns. SpO(2) recordings were at 24-72 hours using Masimo SET Radical-7 on the right hand and left foot. RESULTS: Mean SpO(2) was lower at MA compared to SL in the right hand (97.86 ±1.58 vs 98.28 ±1.41, p =0.05) and left foot (98.49 ±1.35 vs 98.90 ±1.16, p =0.03). No infant with SpO(2) <95% had CCHD. Extrapolating with predicted regression lines set at 95% CI, a SpO(2) cutoff of 95% would result in up to 3.5 times more false positive screens at MA compared to SL. CONCLUSIONS: At MA, SpO(2) is approximately 0.4% lower compared to SL. Our study supports the AAP recommendation suggesting algorithm cutoffs may need adjustment in high-altitude nurseries and suggest broadening it to MA as well. ©2013 The Author(s)/Acta Paediatrica ©2013 Foundation Acta Paediatrica.
Tal Y Samuel; Reuben Bromiker; Francis B Mimouni; Elie Picard; Sigalit Lahav; Dror Mandel; Shmuel Goldberg
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-8
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
©2013 The Author(s)/Acta Paediatrica ©2013 Foundation Acta Paediatrica.
From the Pediatric Pulmonology Unit, Shaare Zedek Medical Center.
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