| The Newborn Lamb as A New Model For Studying Gastroesophageal Reflux. | |
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MedLine Citation:
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PMID: 22722679 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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ABSTRACT: We aimed to determine whether the newborn lamb at term is a valid model for studying gastroesophageal reflux. Seven bottle-fed lambs, aged 2-3 days, underwent esophageal Multichannel Intraluminal Impedance-pH monitoring (MII-pH). A total of 196 reflux episodes were recorded, including 73% alkaline and 27% weakly acid. No acid refluxes were observed. Median bolus clearance time was 4 s [3; 5.5], and proximal reflux extent was 35% (26). This first report of MII-pH in the newborn mammal sets the foundations for future studies with physiological and clinical relevance to human neonates. |
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Authors:
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Djamal Djeddi; Nathalie Samson; Nadia Boudaa; Jean-Paul Praud |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-19 |
Journal Detail:
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Title: Journal of pediatric gastroenterology and nutrition Volume: - ISSN: 1536-4801 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-6-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211545 Medline TA: J Pediatr Gastroenterol Nutr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Neonatal Respiratory Research Unit, Department of Pediatrics and Physiology, Université de Sherbrooke, QC, Canada, J1H 5N4. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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