| New xenograft valved conduit (Contegra) for right ventricular outflow tract reconstruction. | |
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MedLine Citation:
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PMID: 14721819 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The well-known flaws of existing valved conduits for reconstruction of the right ventricular outflow tract (RVOT) continue to stimulate research for the elusive "perfect" conduit. In this study, we describe our experience with a glutaraldehyde-treated bovine jugular vein valved conduit (Contegra). METHODS: 55 years underwent implantation of a Contegra conduit. Diagnoses/procedures included repair of truncus arteriosus (2 patients), pulmonary atresia (3 patients), severe pulmonary insufficiency after prior repair of tetralogy of Fallot (9 patients), and replacement of degenerated valved conduit (1 patient). RESULTS: No operative deaths occurred. One patient required an early conduit replacement for unexplained valve thrombosis. The early postoperative mean transconduit pressure gradient was 7.7+/- 4.9 mm Hg. At a mean follow-up time of 18.5 +/- 6.9 months, all patients were asymptomatic with no discernible calcification in the valve or conduit or significant valve incompetence, while the mean transvalvular gradient remained low (11.1 +/- 4.5 mm Hg). CONCLUSION: The Contegra valved conduit is well suited for RVOT reconstruction, avoids the use of additional foreign material, and remains well functioning during early followup. Nonetheless, the long-term durability remains to be ascertained. |
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Authors:
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Andrew C Chatzis; Nicolas M Giannopoulos; Demetrios Bobos; George B Kirvassilis; Spyros Rammos; George E Sarris |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The heart surgery forum Volume: 6 ISSN: 1522-6662 ISO Abbreviation: Heart Surg Forum Publication Date: 2003 |
Date Detail:
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Created Date: 2004-01-14 Completed Date: 2004-05-04 Revised Date: 2010-03-23 |
Medline Journal Info:
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Nlm Unique ID: 100891112 Medline TA: Heart Surg Forum Country: United States |
Other Details:
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Languages: eng Pagination: 396-8 Citation Subset: IM |
Affiliation:
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Department of Paediatric and Congenital Heart Surgery, Onassis Cardiac Surgery Centre, Athens, Greece. achatzis@otenet.gr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Animals Bioprosthesis* Cattle Child Child, Preschool Female Heart Valve Diseases / surgery Humans Infant Jugular Veins / transplantation* Male Middle Aged Postoperative Complications / surgery Pulmonary Valve Insufficiency / surgery* Reoperation Tetralogy of Fallot / surgery* Thrombosis / surgery Transplantation, Heterologous Ventricular Outflow Obstruction / surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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