| New type of microfabricated carbon electrodes for high-performance liquid chromatography--amperometric detection of fat-soluble vitamins and antioxidants. | |
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MedLine Citation:
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PMID: 18538776 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study evaluates performance of thin-film carbon electrodes prepared by physical vapor deposition of the electrode material on a polyetheretherketone substrate and compares their performance with that of a standard type of glassy carbon electrodes for chromatographic detection cell of thin-layer type. Kaempferol, retinol, retinyl acetate, cholecalciferol, alpha-tocopherol and gamma-tocopherol were selected for the study and their respective detection limits were found to be 0.63, 5.84, 5.91, 28.19, 16.80 and 16.11 pg. The calibration plots were linear for at least three orders of magnitude for all of the six analytes selected for evaluation. Hydrodynamic voltammograms are shown for both types of electrodes for the range of working electrode potentials between +0.40 and +1.40 V. Also shown and discussed are plots of signal-to-noise vs. detection potential. The working electrode potential of +1.30 V was found to be required for an improved long-term stability of detection performance and was suitable for the detection of all six analytes. |
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Authors:
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Jun Cheng; Petr Jandik |
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Publication Detail:
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Type: Journal Article Date: 2008-05-24 |
Journal Detail:
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Title: Journal of chromatography. A Volume: 1198-1199 ISSN: 0021-9673 ISO Abbreviation: J Chromatogr A Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-06-20 Completed Date: 2008-09-22 Revised Date: 2009-01-15 |
Medline Journal Info:
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Nlm Unique ID: 9318488 Medline TA: J Chromatogr A Country: Netherlands |
Other Details:
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Languages: eng Pagination: 148-53 Citation Subset: IM |
Affiliation:
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Research and Development, Dionex Corporation, 1228 Titan Way, Sunnyvale, CA 94088, USA. jun.cheng@dionex.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antioxidants
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analysis,
chemistry* Carbon / chemistry* Cholecalciferol / analysis, chemistry Chromatography, High Pressure Liquid / instrumentation, methods* Electrochemistry Electrodes Fats / chemistry Kaempferols / analysis, chemistry Reproducibility of Results Solubility Vitamin A / analogs & derivatives, analysis, chemistry Vitamins / analysis, chemistry* alpha-Tocopherol / analysis, chemistry gamma-Tocopherol / analysis, chemistry |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Fats; 0/Kaempferols; 0/Vitamins; 0/gamma-Tocopherol; 11103-57-4/Vitamin A; 127-47-9/retinol acetate; 520-18-3/kaempferol; 59-02-9/alpha-Tocopherol; 67-97-0/Cholecalciferol; 7440-44-0/Carbon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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