Document Detail

New trends in pharmacology.
MedLine Citation:
PMID:  331887     Owner:  NLM     Status:  MEDLINE    
Among the factors influencing the arterial blood pressure the neural control through the autonomic nervous system is of paramount significance. The sympathetic division of this system holds a key position in this regard and its neural transmission mechanisms represent a well established target for pharmacological interference aimed at lowering blood pressure. This presentation will first deal with the morphological and physiological basis for blood pressure control through the sympathetic nervous system and the various possibilities for antihypertensive drug action through this system. Special attention will be drawn to recent advances in catecholamine research which may offer new leads in the development of blood pressure lowering agents. A second topic in this review will be some remarks on other pharmacological principles for interference with vascular control apart from the sympathetic system, particularly the vasodilator principle.
M Henning
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta medica Scandinavica. Supplementum     Volume:  606     ISSN:  0365-463X     ISO Abbreviation:  Acta Med. Scand. Suppl.     Publication Date:  1977  
Date Detail:
Created Date:  1977-10-28     Completed Date:  1977-10-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370331     Medline TA:  Acta Med Scand Suppl     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  87-93     Citation Subset:  IM    
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MeSH Terms
Antihypertensive Agents / pharmacology*,  therapeutic use
Blood Pressure / drug effects
Catecholamines / physiology
Hypertension / drug therapy
Sensory Receptor Cells / drug effects
Sympathetic Nervous System / physiology
Vasodilator Agents / pharmacology,  therapeutic use
Reg. No./Substance:
0/Antihypertensive Agents; 0/Catecholamines; 0/Vasodilator Agents

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