| New treatment options for acute coronary syndromes. | |
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MedLine Citation:
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PMID: 17203988 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Complications from atherosclerotic coronary artery disease are the principal cause of death worldwide. Many therapeutic strategies have been developed to reduce the burden of this disease. Systemic antithrombotic therapy, typically with unfractionated heparin, has long been a mainstay in the management of acute coronary syndromes (ACS) despite several limitations, including intravenous administration and unpredictable pharmacokinetics necessitating frequent monitoring. In recent years, newer agents without these limitations have been developed and evaluated in clinical trials. This review focuses on novel antithrombotic therapies for ACS, particularly fondaparinux sodium, a synthetic inhibitor of clotting factor Xa. |
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Authors:
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Charles L Campbell |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The American journal of managed care Volume: 12 ISSN: 1088-0224 ISO Abbreviation: Am J Manag Care Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2007-01-05 Completed Date: 2007-04-16 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9613960 Medline TA: Am J Manag Care Country: United States |
Other Details:
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Languages: eng Pagination: S435-43 Citation Subset: H |
Affiliation:
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University of Kentucky, Gill Heart Institute, 900 S Limestone St, 326 Charles T. Wethington Bldg, Lexington, KY 40536-0200, USA. clcampbell@uky.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Coronary Artery Disease / drug therapy* Fibrinolytic Agents / therapeutic use* Humans United States |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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