| New transmitters and new targets in the autonomic nervous system. | |
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MedLine Citation:
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PMID: 7907243 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Several recent findings have made research into the autonomic nervous system even more exciting, such as the revelation that nitric oxide is a major neurotransmitter, the delineation of the physiological roles for purines and vasoactive intestinal peptide, and the discovery that the interstitial cells of Cajal are major target cells for enteric innervation. Nitric oxide is probably the major neurotransmitter evoking inhibitory junction potentials in smooth muscle. ATP is a mediator of non-adrenergic non-cholinergic enteric innervation, as well as being a fast neurotransmitter in peripheral and autonomic neuro-neuronal synapses. The interactions between enteric nerves and both immune cells and interstitial cells of Cajal (as pacemaker cells of gut smooth muscle) are forcing a rethink of many aspects of gut physiology. |
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Authors:
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C Barajas-López; J D Huizinga |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Current opinion in neurobiology Volume: 3 ISSN: 0959-4388 ISO Abbreviation: Curr. Opin. Neurobiol. Publication Date: 1993 Dec |
Date Detail:
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Created Date: 1994-04-12 Completed Date: 1994-04-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9111376 Medline TA: Curr Opin Neurobiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1020-7 Citation Subset: IM |
Affiliation:
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Department of Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Autonomic Nervous System / physiology* Humans Neurotransmitter Agents / physiology* |
| Chemical | |
Reg. No./Substance:
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0/Neurotransmitter Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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