Document Detail

New therapeutic strategies for the treatment of patent ductus arteriosus.
MedLine Citation:
PMID:  21942587     Owner:  NLM     Status:  Publisher    
In the present manuscript we will focus our attention on the drug choice and its dosage.some studies suggest that the failure of pharmacologic pda closure might be due to the inadequacy of the standard dose regimen, because of large interindividual pharmacokinetics and pharmacodynamic variations in premature infants. we discuss the possibility that the early treatment of pda with ibuprofen doses higher than those actually recommended might increase the closure rate in preterm infants.
Carlo Dani
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Publication Detail:
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  24     ISSN:  1476-4954     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  32-33     Citation Subset:  -    
Department of Medical and Surgical Critical Care, Section of Neonatology, Careggi University Hospital of Florence.
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