Document Detail

New therapeutic approaches for resistant hypertension.
MedLine Citation:
PMID:  22362551     Owner:  NLM     Status:  Publisher    
In the past few years, 2 new procedures have been developed for the treatment of resistant hypertension: electrical stimulation of carotid baroreceptors and catheter-based renal denervation. Both of these procedures have a solid pathophysiological background, which is based on the evidence that carotid baroreceptors and renal nerves are involved in the pathogenesis of different forms of experimental hypertension, potentiating sympathetic cardiovascular influence and thus promoting the development and progression of elevated blood pressure values. This paper will review the results of the clinical trials performed so far making use of each of the 2 above-mentioned approaches. The pros and cons of each intervention as well as the questions that remain to be addressed in the future will also be discussed.
Guido Grassi; Giuseppe Mancia
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-22
Journal Detail:
Title:  Journal of nephrology     Volume:  -     ISSN:  1724-6059     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9012268     Medline TA:  J Nephrol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  0     Citation Subset:  -    
Department of Internal Medicine, S. Gerardo Hospital, Monza, University of Milano-Bicocca, Milan - Italy; and Multimedica IRCCS, Sesto San Giovanni, Milan - Italy.
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