| New synthetic protocols for the preparation of unsymmetrical bisindoles. | |
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MedLine Citation:
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PMID: 17134266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Novel unsymmetrical bisindoles were synthesized by a solvent-free C-C bond-formation reaction under mild conditions. Starting from aziridines or hydroxyl precursors, indoles have been used as C-nucleophiles to form new pharmacologically interesting bisindoles via an electrophilic aromatic substitution pathway in good to excellent yields. [reaction: see text] |
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Authors:
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Hanns Martin Kaiser; Wei Fun Lo; Abdol Majid Riahi; Anke Spannenberg; Matthias Beller; Man Kin Tse |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Organic letters Volume: 8 ISSN: 1523-7060 ISO Abbreviation: Org. Lett. Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-11-30 Completed Date: 2007-08-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
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Languages: eng Pagination: 5761-4 Citation Subset: IM |
Affiliation:
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Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, D-18059 Rostock, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aziridines
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chemistry Catalysis Crystallization Crystallography, X-Ray Hydroxyl Radical Indoles / chemical synthesis*, chemistry Staurosporine / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Aziridines; 0/Indoles; 3352-57-6/Hydroxyl Radical; 62996-74-1/Staurosporine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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