Document Detail

New surprises in genetic coding and how an ingenious experiment was almost scooped, by evolution.
MedLine Citation:
PMID:  16940146     Owner:  NLM     Status:  MEDLINE    
In 1962, one of the most creative and cogent experiments on the protein coding problem was published. Now it has been discovered that archaebacteria had been doing a related kind of "experiment" all along. Both involve a trick: changing an amino acid that is already attached to a "correct" transfer RNA.
Thoru Pederson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  FASEB journal : official publication of the Federation of American Societies for Experimental Biology     Volume:  20     ISSN:  1530-6860     ISO Abbreviation:  FASEB J.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-30     Completed Date:  2006-09-18     Revised Date:  2012-02-15    
Medline Journal Info:
Nlm Unique ID:  8804484     Medline TA:  FASEB J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1759-60     Citation Subset:  IM    
Department of Biochemistry and Molecular Pharmacology, Program in Cell Dynamics, University of Massachusetts Medical School, 377 Plantation St., Worcester, MA 01605, USA.
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MeSH Terms
Archaea / genetics
Evolution, Molecular*
Genetic Code*
RNA, Archaeal / genetics
RNA, Transfer / genetics
RNA, Transfer, Amino Acid-Specific / genetics
Reg. No./Substance:
0/RNA, Archaeal; 0/RNA, Transfer, Amino Acid-Specific; 9014-25-9/RNA, Transfer

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