Document Detail


New subtraction algorithms for evaluation of lesions on dynamic contrast-enhanced MR mammography.
MedLine Citation:
PMID:  12439585     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report new subtraction algorithms for the detection of lesions in dynamic contrast-enhanced MR mammography(CE MRM). Twenty-five patients with suspicious breast lesions underwent dynamic CE MRM using 3D fast low-angle shot. After the acquisition of the T1-weighted scout images, dynamic images were acquired six times after the bolus injection of contrast media. Serial subtractions, step-by-step subtractions, and reverse subtractions, were performed. Two radiologists attempted to differentiate benign from malignant lesion in consensus. The sensitivity, specificity, and accuracy of the method leading to the differentiation of malignant tumor from benign lesions were 85.7, 100, and 96%, respectively. Subtraction images allowed for better visualization of the enhancement as well as its temporal pattern than visual inspection of dynamic images alone. Our findings suggest that the new subtraction algorithm is adequate for screening malignant breast lesions and can potentially replace the time-intensity profile analysis on user-selected regions of interest.
Authors:
Byung Gil Choi; Hak Hee Kim; Euy Neyng Kim; Bum-soo Kim; Ji-Youn Han; Seung-Schik Yoo; Seog Hee Park
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2002-04-30
Journal Detail:
Title:  European radiology     Volume:  12     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2002-11-19     Completed Date:  2003-03-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  3018-22     Citation Subset:  IM    
Affiliation:
Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul. cbg@catholic.ac.kr
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Algorithms
Artifacts
Biopsy, Needle
Breast Neoplasms / diagnosis*,  pathology
Carcinoma, Ductal, Breast / diagnosis*,  pathology
Diagnosis, Differential
Electrocardiography
Female
Follow-Up Studies
Granuloma / diagnosis*,  pathology
Humans
Magnetic Resonance Imaging*
Mammography / methods*
Middle Aged
Neoplasm Invasiveness
Prospective Studies
Radiographic Image Enhancement*
Sensitivity and Specificity
Subtraction Technique
Time Factors
Women's Health

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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