Document Detail


New quaternary ammonium compounds with adrenomimetic action.
MedLine Citation:
PMID:  14415358     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quaternary salts of two triesters of p-dimethylaminothiophenol and phosphoric acid or thiophosphoric acid have effects similar to epinephrine on blood pressure, heart rate, and the nictitating membrane of the anesthetized cat. Two analogous compounds derived from phenol are depressor. None is a potent anticholinesterase. Further investigation is desirable because of the possibility of a relatively specific action on sympathetic ganglia.
Authors:
R A LEHMAN; H A JEWELL
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  131     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1960 Jun 
Date Detail:
Created Date:  1960-12-01     Completed Date:  1998-11-01     Revised Date:  2011-12-02    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  1885-6     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Phosphates / pharmacology*
Sympathomimetics / pharmacology*
Chemical
Reg. No./Substance:
0/Phosphates; 0/Sympathomimetics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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