| New perspectives in cell delivery systems for tissue regeneration: natural-derived injectable hydrogels. | |
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MedLine Citation:
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PMID: 22865572 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Natural polymers, because of their biocompatibility, availability, and physico-chemical properties have been the materials of choice for the fabrication of injectable hydrogels for regenerative medicine. In particular, they are appealing materials for delivery systems and provide sustained and controlled release of drugs, proteins, gene, cells, and other active biomolecules immobilized.In this work, the use of hydrogels obtained from natural source polymers as cell delivery systems is discussed. These materials were investigated for the repair of cartilage, bone, adipose tissue, intervertebral disc, neural, and cardiac tissue. Papers from the last ten years were considered, with a particular focus on the advances of the last five years. A critical discussion is centered on new perspectives and challenges in the regeneration of specific tissues, with the aim of highlighting the limits of current systems and possible future advancements. |
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Authors:
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Fabiola Munarin; Paola Petrini; Sabrina Bozzini; Maria Cristina Tanzi |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-2 |
Journal Detail:
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Title: Journal of applied biomaterials & functional materials Volume: - ISSN: 2280-8000 ISO Abbreviation: J Appl Biomater Function Mater Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101586617 Medline TA: J Appl Biomater Function Mater Country: - |
Other Details:
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Languages: ENG Pagination: 0 Citation Subset: - |
Affiliation:
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Biomatlab, Bioengineering Department, Politecnico di Milano, Milan - Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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