Document Detail


New perspectives in cell delivery systems for tissue regeneration: natural-derived injectable hydrogels.
MedLine Citation:
PMID:  22865572     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Natural polymers, because of their biocompatibility, availability, and physico-chemical properties have been the materials of choice for the fabrication of injectable hydrogels for regenerative medicine. In particular, they are appealing materials for delivery systems and provide sustained and controlled release of drugs, proteins, gene, cells, and other active biomolecules immobilized.In this work, the use of hydrogels obtained from natural source polymers as cell delivery systems is discussed. These materials were investigated for the repair of cartilage, bone, adipose tissue, intervertebral disc, neural, and cardiac tissue. Papers from the last ten years were considered, with a particular focus on the advances of the last five years. A critical discussion is centered on new perspectives and challenges in the regeneration of specific tissues, with the aim of highlighting the limits of current systems and possible future advancements.
Authors:
Fabiola Munarin; Paola Petrini; Sabrina Bozzini; Maria Cristina Tanzi
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2012-09-27
Journal Detail:
Title:  Journal of applied biomaterials & functional materials     Volume:  10     ISSN:  2280-8000     ISO Abbreviation:  J Appl Biomater Funct Mater     Publication Date:  2012  
Date Detail:
Created Date:  2012-09-27     Completed Date:  2013-09-18     Revised Date:  2014-10-21    
Medline Journal Info:
Nlm Unique ID:  101586617     Medline TA:  J Appl Biomater Funct Mater     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  67-81     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / physiology
Biocompatible Materials / chemistry,  pharmacology*
Bone Regeneration / drug effects
Cartilage / physiology
Humans
Hydrogels / chemistry,  pharmacology*
Intervertebral Disc / physiology
Neurons / physiology
Regeneration / drug effects*
Regenerative Medicine
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 0/Hydrogels
Comments/Corrections
Erratum In:
J Appl Biomater Funct Mater. 2013;11(1):e71

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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