Document Detail


New patient-applied therapy for anogenital warts is rated favourably by patients.
MedLine Citation:
PMID:  11516364     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our objective was to determine patient attitudes to having genital warts, and their perceptions of their treatment with imiquimod and other therapies. As an adjunct to a clinical trial in which patients with external genital warts were treated with imiquimod 5% cream until their warts cleared or for up to 16 weeks, quantitative questionnaires consisting of multiple choice questions and 5-point rating scales were completed prior to, and at the end, of the study period. Pre-study and post-study questionnaires were completed by 902 and 629 patients, respectively. Patients expressed a definite concern about genital warts. The majority of patients (70%) had been previously treated for genital warts, and expressed dissatisfaction with their previous therapies. Of patients treated with imiquimod in this study, 82% reported that their warts decreased in size; this occurred within the first 4 weeks for 78% of patients. Sixty-one per cent of patients perceived that their warts completely cleared within the 16-week treatment period. Patients rated imiquimod 5% cream as better than other genital wart therapies in terms of overall satisfaction, time to clearance, convenience and lack of associated pain. In conclusion, patients rated imiquimod 5% cream as an effective treatment which clears warts in an acceptable length of time causing minimal pain and is convenient to use.
Authors:
C O'Mahony; C Law; H P Gollnick; M Marini
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of STD & AIDS     Volume:  12     ISSN:  0956-4624     ISO Abbreviation:  Int J STD AIDS     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-08-22     Completed Date:  2001-10-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9007917     Medline TA:  Int J STD AIDS     Country:  England    
Other Details:
Languages:  eng     Pagination:  565-70     Citation Subset:  IM; X    
Affiliation:
Department of Genito-Urinary Medicine, The Countess of Chester Hospital, Countess of Chester Health Park, Liverpool Road, Chester CH2 1UL, UK. dr.o'mahony@coch-tr.nwest.nhs.uk
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Adolescent
Adult
Aminoquinolines / administration & dosage,  therapeutic use*
Antineoplastic Agents / administration & dosage,  therapeutic use*
Anus Neoplasms / drug therapy*,  pathology
Female
Follow-Up Studies
Genital Neoplasms, Female / drug therapy*,  pathology
Genital Neoplasms, Male / drug therapy*,  pathology
Health Knowledge, Attitudes, Practice
Humans
Male
Questionnaires
Time Factors
Treatment Outcome
Warts / drug therapy*,  pathology
Chemical
Reg. No./Substance:
0/Aminoquinolines; 0/Antineoplastic Agents; 99011-02-6/imiquimod

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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