| New oral anticoagulants: a brief review. | |
| | |
MedLine Citation:
|
PMID: 19326634 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This manuscript represents a brief review of the current oral anticoagulants that have come on the scene over the past decade and that are now in various stages of development through the process of phase II and III clinical trials. A brief review of the oral thrombin and direct factor Xa inhibitors is presented to apprise the practicing clinician of the status of these new agents. Efficacy and safety issues are mentioned as they relate to each agent and the need for alternative agents to replace the vitamin K antagonists for long-term anticoagulation therapy. Although none of the agents discussed in the review have been approved for clinical use, data accumulated thus far from the clinical studies have provided some degree of encouragement and optimism for their future approval. |
| | |
Authors:
|
Joseph J Mazza; Steven H Yale |
Related Documents
:
|
21999904 - A systematic meta-review grading the evidence for non-genetic risk factors and putative... 1291384 - Clinical aspects of occlusion: 1. occlusal terminology and the conformative approach. 20721574 - The clinical spectrum of late-onset alexander disease: a systematic literature review. 2220314 - Transient global amnesia and raynaud's phenomenon in scleroderma. 6497794 - Gastric retention associated with a pyloric mass in two horses. 2812824 - Acute mediastinitis. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: WMJ : official publication of the State Medical Society of Wisconsin Volume: 108 ISSN: 1098-1861 ISO Abbreviation: WMJ Publication Date: 2009 Feb |
Date Detail:
|
Created Date: 2009-03-30 Completed Date: 2009-05-08 Revised Date: 2009-05-14 |
Medline Journal Info:
|
Nlm Unique ID: 9716054 Medline TA: WMJ Country: United States |
Other Details:
|
Languages: eng Pagination: 35-9 Citation Subset: IM |
Affiliation:
|
Departments of Hematology/Oncology, Marshfield Clinic and Clinical Research Center, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA. mazza.joseph@mcrf.mfldclin.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Administration, Oral Anticoagulants / administration & dosage*, adverse effects, therapeutic use* Clinical Trials as Topic Humans Safety Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Anticoagulants |
| Comments/Corrections | |
Erratum In:
|
WMJ. 2009 Apr;108(2):84 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Medical information and the use of emerging technologies.
Next Document: A review of the effects of martial arts practice on health.