Document Detail

New onset and persistent symptoms of post-traumatic stress disorder self reported after deployment and combat exposures: prospective population based US military cohort study.
MedLine Citation:
PMID:  18198395     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe new onset and persistence of self reported post-traumatic stress disorder symptoms in a large population based military cohort, many of whom were deployed in support of the wars in Iraq and Afghanistan.
DESIGN: Prospective cohort analysis.
SETTING AND PARTICIPANTS: Survey enrolment data from the millennium cohort (July 2001 to June 2003) obtained before the wars in Iraq and Afghanistan. Follow-up (June 2004 to February 2006) data on health outcomes collected from 50 184 participants.
MAIN OUTCOME MEASURES: Self reported post-traumatic stress disorder as measured by the posttraumatic stress disorder checklist-civilian version using Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria.
RESULTS: More than 40% of the cohort were deployed between 2001 and 2006; between baseline and follow-up, 24% deployed for the first time in support of the wars in Iraq and Afghanistan. New incidence rates of 10-13 cases of post-traumatic stress disorder per 1000 person years occurred in the millennium cohort. New onset self reported post-traumatic stress disorder symptoms or diagnosis were identified in 7.6-8.7% of deployers who reported combat exposures, 1.4-2.1% of deployers who did not report combat exposures, and 2.3-3.0% of non-deployers. Among those with self reported symptoms of post-traumatic stress disorder at baseline, deployment did not affect persistence of symptoms.
CONCLUSIONS: After adjustment for baseline characteristics, these prospective data indicate a threefold increase in new onset self reported post-traumatic stress disorder symptoms or diagnosis among deployed military personnel who reported combat exposures. The findings define the importance of post-traumatic stress disorder in this population and emphasise that specific combat exposures, rather than deployment itself, significantly affect the onset of symptoms of post-traumatic stress disorder after deployment.
Tyler C Smith; Margaret A K Ryan; Deborah L Wingard; Donald J Slymen; James F Sallis; Donna Kritz-Silverstein;
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2008-01-15
Journal Detail:
Title:  BMJ (Clinical research ed.)     Volume:  336     ISSN:  1756-1833     ISO Abbreviation:  BMJ     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-15     Completed Date:  2008-03-19     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  8900488     Medline TA:  BMJ     Country:  England    
Other Details:
Languages:  eng     Pagination:  366-71     Citation Subset:  AIM; IM    
Department of Defense Center for Deployment Health Research at the Naval Health Research Center, San Diego, CA 92106, USA.
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MeSH Terms
Acute Disease
Chronic Disease
Combat Disorders / epidemiology*
Middle Aged
Military Medicine
Prospective Studies
Risk Factors
United States
Comment In:
Evid Based Ment Health. 2008 Nov;11(4):126   [PMID:  18952975 ]

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