Document Detail

New occlusive agent for therapeutic embolization tested in dogs.
MedLine Citation:
PMID:  6329515     Owner:  NLM     Status:  MEDLINE    
A new occlusive agent, Vilan 500, was used to embolize the arterial bed of the kidney in 12 dogs. This polyvinyl acetate, alcohol-soluble agent becomes gelantinous on contact with an aqueous environment and its low viscosity makes this material well suited for application through small-caliber catheters. Complete arterial occlusion of the embolized kidneys was observed in all animals. On histologic examination of tissue 4-6 weeks after the procedure, changes were seen such as shrinkage through fibrosis, diffuse necrosis and atrophic parenchyma. No signs of recanalization of the embolized artery or functional collateral circulation were noted in any dog.
J H Peregrin; M Kaspar; M Haco; R Vanĕcek; A Belán
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular and interventional radiology     Volume:  7     ISSN:  0174-1551     ISO Abbreviation:  Cardiovasc Intervent Radiol     Publication Date:  1984  
Date Detail:
Created Date:  1984-07-31     Completed Date:  1984-07-31     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8003538     Medline TA:  Cardiovasc Intervent Radiol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  97-101     Citation Subset:  IM    
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MeSH Terms
Embolization, Therapeutic*
Iodized Oil / administration & dosage
Polyvinyls / administration & dosage,  therapeutic use*
Renal Artery / radiography
Reg. No./Substance:
0/Polyvinyls; 8001-40-9/Iodized Oil; 9003-20-7/polyvinyl acetate

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