Document Detail


New norms for a new generation: cognitive performance in the framingham offspring cohort.
MedLine Citation:
PMID:  15371099     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A previous publication presented normative data on neuropsychological tests stratified by age, gender, and education based on the Original Cohort of the Framingham Heart Study. Many contemporary investigations include subject samples with higher levels of education, a factor known to affect cognitive performance. Secular change in education prompted the reexamination of norms in the children of the Original Cohort. The study population consisted of 853 men and 988 women from the Offspring Study, free of clinical neurological disease, who underwent a neuropsychological examination, which included tests given to their parents in 1974 to 1976 as well as additional newer tests to provide a more comprehensive battery. The Offspring population overall was more evenly distributed by gender and better educated. Their performance on cognitive tests was superior to that of the Original Cohort. Multivariable analyses revealed that more years of education explained only a part of the cohort differences. These findings suggest that continued surveillance of each generation is necessary to document the impact that unique social and economic variables have on cognitive function. Here, the authors provide updated normative data.
Authors:
Rhoda Au; Sudha Seshadri; Philip A Wolf; Merrill Elias; Penelope Elias; Lisa Sullivan; Alexa Beiser; Ralph B D'Agostino
Related Documents :
25352519 - Aerobic fitness and intraindividual reaction time variability in middle and old age.
22507349 - Biomechanical evaluation of the relationship between postural control and body mass index.
1165289 - Shifts in perceptual differentiation and defense mechanisms in alcoholics.
17405119 - Health-status of adult survivors of childhood cancer: a large-scale population-based st...
25230099 - Increased variability of lap speeds differentiate medallists and non-medallists in midd...
9052319 - A comparison of traditional textbook and interactive computer learning of neuromuscular...
4075779 - Social dominance, reproduction, and release of the maturation-delaying chemosignal in t...
529839 - Differences between transfer rna methylase activity in human diploid fibroblasts during...
16688209 - Association among hypogonadism, quality of life and erectile dysfunction in middle-aged...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Experimental aging research     Volume:  30     ISSN:  0361-073X     ISO Abbreviation:  Exp Aging Res     Publication Date:    2004 Oct-Dec
Date Detail:
Created Date:  2004-09-16     Completed Date:  2005-02-25     Revised Date:  2008-02-25    
Medline Journal Info:
Nlm Unique ID:  7603335     Medline TA:  Exp Aging Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  333-58     Citation Subset:  IM    
Affiliation:
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118-2526, USA. rhodaau@bu.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult Children
Aged
Aging / physiology*
Cognition*
Cohort Effect
Educational Status
Female
Humans
Male
Middle Aged
Neuropsychological Tests / standards*
Regression Analysis
Sex Factors
Grant Support
ID/Acronym/Agency:
5R01-AG 08122/AG/NIA NIH HHS; 5R01-AG16495-03/AG/NIA NIH HHS; 5R01-NS17950-19/NS/NINDS NIH HHS; N01-HC-25195/HC/NHLBI NIH HHS
Comments/Corrections
Comment In:
Exp Aging Res. 2007 Jul-Sep;33(3):205-71   [PMID:  17497370 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Changes in posed facial expression of emotion across the adult life span.
Next Document:  The salience of linguistic clauses in young and older adults' running memory for speech.