| New multifunctional surfactants from natural phenolic acids. | |
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MedLine Citation:
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PMID: 22142033 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We synthesized several new multifunctional molecules derived from natural sources such as amino acids and hydroxycinnamic acids. They exhibit various activities such as emulsifying, UV-protecting and radical scavenging, thereby conforming to the latest requirements for cosmetic ingredients. The synthesis comprises only a few steps: i) the amino acid, whose acid group(s) are protected by esterification, is coupled with ferulic or caffeic acid; ii) the p-hydroxyl group of the cinnamic derivative reacts with dodecyl bromide in the presence of potassium carbonate; the resulting compounds are highly lipophilic and tested as water/oil (w/o) emulsifiers; iii) these molecules, by de-protonating the acid groups of the amino acids, with successive salification, are more hydrophilic, with stronger o/w emulsifying properties. The new multifunctional surfactants might prove useful for the treatment of multiple skin conditions, including loss of cellular antioxidants, damage from free radicals, damage from UV, and others. |
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Authors:
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Marisanna Centini; Maria Sole Rossato; Alessandro Sega; Anna Buonocore; Sara Stefanoni; Cecilia Anselmi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-5 |
Journal Detail:
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Title: Journal of agricultural and food chemistry Volume: - ISSN: 1520-5118 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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