| New method for quantitating the medial component of pulmonary arteries. Factors affecting the measurements. | |
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MedLine Citation:
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PMID: 3839657 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The study objectives were to determine the effect of several factors related to tissue preparation on the relationship between medial area and size of the muscular pulmonary artery (defined in terms of total length of internal elastic lamina). This relationship took the form y = Axb that was linearized by plotting the square root of medial area against artery size. Complete distention of pulmonary arteries by an injection medium caused the internal elastic lamina to stretch by a factor of approximately 1.5. The relationship between medial area and artery size was unaffected by either the pressure method used for lung inflation/fixation or the tissue-embedding medium. Tissue shrinkage was considerable with paraffin embedding and negligible with glycol methacrylate. More arteries were considered measurable in glycol methacrylate-embedded tissue. |
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Authors:
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J M Fernie; A McLean; D Lamb |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Archives of pathology & laboratory medicine Volume: 109 ISSN: 0003-9985 ISO Abbreviation: Arch. Pathol. Lab. Med. Publication Date: 1985 Sep |
Date Detail:
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Created Date: 1985-09-26 Completed Date: 1985-09-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7607091 Medline TA: Arch Pathol Lab Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 843-8 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Autopsy Female Fixatives Humans Injections Male Methacrylates Middle Aged Muscle, Smooth, Vascular / anatomy & histology Paraffin Pressure Pulmonary Artery / anatomy & histology* Specimen Handling |
| Chemical | |
Reg. No./Substance:
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0/Fixatives; 0/Methacrylates; 8002-74-2/Paraffin; 868-77-9/hydroxyethyl methacrylate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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