| New insights to primary photodynamic effects--Singlet oxygen kinetics in living cells. | |
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MedLine Citation:
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PMID: 20117016 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The kinetics of chemical singlet oxygen quencher consumption inside living cells during low dose illumination was revealed via time resolved singlet oxygen luminescence detection. Deviations of the measured data from the common theoretical model for (1)O(2) kinetics forced the authors to consider a one-dimensional diffusion model for description of the kinetics of singlet oxygen generated by membrane localized photosensitizers. Our observations reconcile seemingly contradictory reports presenting different values for the efficiency of singlet oxygen interaction with cells. |
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Authors:
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Steffen Hackbarth; Jan Schlothauer; Annegret Preuss; Beate R?der |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-12-21 |
Journal Detail:
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Title: Journal of photochemistry and photobiology. B, Biology Volume: 98 ISSN: 1873-2682 ISO Abbreviation: J. Photochem. Photobiol. B, Biol. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-08 Completed Date: 2010-06-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804966 Medline TA: J Photochem Photobiol B Country: Switzerland |
Other Details:
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Languages: eng Pagination: 173-9 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier B.V. All rights reserved. |
Affiliation:
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Humboldt-Universit?t zu Berlin, Institute of Physics, Photobiophysics, Newtonstr. 15, 12489 Berlin, Germany. hacky@physik.hu-berlin.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Computer Simulation Humans Jurkat Cells Kinetics Light Liposomes / chemistry*, radiation effects* Models, Biological* Models, Chemical* Photosensitizing Agents / administration & dosage, chemistry* Singlet Oxygen / chemistry*, metabolism*, radiation effects |
| Chemical | |
Reg. No./Substance:
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0/Liposomes; 0/Photosensitizing Agents; 17778-80-2/Singlet Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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