Document Detail


New insights into target organ involvement in hypertension.
MedLine Citation:
PMID:  19427491     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hypertension and its sequelae are complex processes. Optimization of the care of the hypertensive patient requires not only attention to the regulation of arterial pressure but also attention to blunting the hypertension-related processes that lead to vascular disease. It is clear that the regulation of these processes is much more complex than previously understood. Here several new insights into the pathogenesis of hypertension-related vascular disease have been explored. While this review is not exhaustive, it does serve to point out the varied nature of the biologic processes that must be taken into account and it points to new avenues for the development of therapeutic agents.
Authors:
Richard N Re
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Medical clinics of North America     Volume:  93     ISSN:  1557-9859     ISO Abbreviation:  Med. Clin. North Am.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-11     Completed Date:  2009-06-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985236R     Medline TA:  Med Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  559-67     Citation Subset:  AIM; IM    
Affiliation:
Ochsner Clinic Foundation, New Orleans, LA 70121, USA. rre@ochsner.org
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Humans
Hypertension / complications*,  physiopathology
Receptor, Angiotensin, Type 1 / drug effects,  metabolism
Receptors, Cell Surface / metabolism
Renin-Angiotensin System* / drug effects,  physiology
Transforming Growth Factors / physiology
Vascular Diseases / etiology,  physiopathology
Chemical
Reg. No./Substance:
0/Receptor, Angiotensin, Type 1; 0/Receptors, Cell Surface; 0/prorenin receptor; 76057-06-2/Transforming Growth Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hypertension: reflections on risks and prognostication.
Next Document:  The renin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative ...