| New insights into experimental evidence on atelectasis and causes of lung injury. | |
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MedLine Citation:
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PMID: 20608555 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Development of atelectasis is common in both patients with and without lung injury during mechanical ventilation. Atelectasis might contribute to or attenuate lung injury by different possible mechanisms. Possible direct effects of atelectasis include inflammatory activation or infection of the affected regional lung tissues. In addition, the loss of aerated lung volume due to atelectasis in mechanically ventilated patients indirectly results in increased mechanical strain of the reduced number of ventilated lung regions, if ventilation is not adequately decreased. This study discusses possible mechanisms and interactions between atelectasis formation in the lungs and the development or aggravation of acute lung injury. |
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Authors:
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Thomas Muders; Hermann Wrigge |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Best practice & research. Clinical anaesthesiology Volume: 24 ISSN: 1521-6896 ISO Abbreviation: Best Pract Res Clin Anaesthesiol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2010-07-22 Revised Date: 2011-04-28 |
Medline Journal Info:
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Nlm Unique ID: 101121446 Medline TA: Best Pract Res Clin Anaesthesiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 171-82 Citation Subset: IM |
Affiliation:
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Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Lung Injury
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etiology*,
physiopathology Animals Disease Models, Animal Humans Pulmonary Atelectasis / complications*, etiology Respiration, Artificial / adverse effects* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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