| New insights in research about acute ischemic myocardial injury and inflammation. | |
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MedLine Citation:
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PMID: 23286292 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Recognition that inflammation may contribute to the pathogenesis of various cardiac diseases has naturally led to the evaluation of the therapeutic potential of a range of anti-inflammatory approaches. Unfortunately, results in most settings have been disappointing. The majority of novel approaches fail despite promising preclinical data, partly attributable to off-target effects. The purpose of this review, focused on inflammation following acute myocardial ischemia, is to give a brief overview of the new insights regarding research on pro-inflammatory signaling cascades that could be targeted for cardioprotective therapeutic developments. |
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Authors:
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Anne Vincent; Benoit Lattuca; Nolwenn Merlet; Catherine Sportouch-Dukhan; Stéphanie Barrère-Lemaire |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-31 |
Journal Detail:
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Title: Anti-inflammatory & anti-allergy agents in medicinal chemistry Volume: - ISSN: 1875-614X ISO Abbreviation: Antiinflamm Antiallergy Agents Med Chem Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2013-1-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101462262 Medline TA: Antiinflamm Antiallergy Agents Med Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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CNRS, UMR-5203, Institut de Génomique Fonctionnelle, Montpellier, F-34094, France. anne.vincent@igf.cnrs.fr. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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