| New insights about delayed allergic hypersensitivity to corticosteroids. | |
| | |
MedLine Citation:
|
PMID: 22370569 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Corticosteroids are among the most commonly used drugs, both topically and systemically. Although unexpected and paradoxical, allergic hypersensitivity to corticosteroids is a common finding, delayed-type reactions being much more frequently encountered than the immediate-type ones. With regard to cross-reactions between corticosteroids, based on patch-test results and molecular modelling, we were recently able to simplify the previous classification into 3 different groups, i.e., Group 1: the non-methylated, most often non-halogenated molecules (Group A, D2 and budesonide), which produce most of the allergic reactions; Group 2: the halogenated molecules with a C16/C17 cis ketal/diol structure (acetonide Group B); and Group 3: the halogenated and C16-methylated molecules (Group C and D1) that only rarely produce allergy. |
| | |
Authors:
|
M Baeck; A Goossens |
Related Documents
:
|
20725859 - Homochiral selectivity in rna synthesis: montmorillonite-catalyzed quaternary reactions... 22577939 - Characterization of the function of cytoglobin as an oxygen-dependent regulator of nitr... 181359 - Pathway of thiamine pyrophosphate synthesis in micrococcus denitrificans. 6694909 - Total synthesis of certain 2-, 6-mono- and 2,6-disubstituted-tubercidin derivatives. sy... 22287209 - Homogeneous photocatalytic reactions with organometallic and coordination compounds-per... 22907889 - Dondorff rings: synthesis, isolation, and properties of 60°-directed bisterpyridine-ba... 19913449 - Ultrasound promoted rapid and green synthesis of 1,8-dioxo-octahydroxanthenes derivativ... 21837649 - Ocular hypotensive action of a novel tetrahydroquinoline analog in rabbit: physicochemi... 11073689 - Effect of solvent on aggregation and reactivity of two lithium enolates(1) |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia Volume: 147 ISSN: 0392-0488 ISO Abbreviation: G Ital Dermatol Venereol Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-02-28 Completed Date: 2012-07-03 Revised Date: 2012-07-30 |
Medline Journal Info:
|
Nlm Unique ID: 8102852 Medline TA: G Ital Dermatol Venereol Country: Italy |
Other Details:
|
Languages: eng Pagination: 65-9 Citation Subset: IM |
Affiliation:
|
Departement of Dermatology, Saint-Luc University Clinic, Louvain Catholic University, Bruxelles, Belgium. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenal Cortex Hormones
/
adverse effects*,
classification,
metabolism Drug Eruptions / etiology* Drug Hypersensitivity / etiology* Halogenation Humans Hypersensitivity, Delayed / chemically induced*, immunology* |
| Chemical | |
Reg. No./Substance:
|
0/Adrenal Cortex Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cosmetic applications of sclerotherapy.
Next Document: Atopic dermatitis (AD) management in an Italian pediatric clinic.