Document Detail

New hemodynamic test for assessment of failing hemodialysis grafts: the saline infusion test.
MedLine Citation:
PMID:  10716386     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To validate the saline infusion test, a new hemodynamic test for assessment of failing hemodialysis access grafts. MATERIALS AND METHODS: Over a 12-month period, 31 procedures were performed in 25 patients with synthetic forearm loop grafts for hemodialysis. Pre- and postangioplasty measurements of static graft pressures and infusion pressures were obtained. For the saline infusion test, graft pressure was measured while saline was infused at a rate of 600 mL/min for 10 seconds with arterial inflow occluded. Comparison was made to percent outflow stenosis as determined with pre- and postangioplasty angiograms. RESULTS: There was no correlation between either the static intragraft pressure (r = .085, P = .654) or the normalized pressure ratio (r = .136, P = .4676) and venous outflow stenosis in the preangioplasty group. When pressure was measured during infusion, a significant Pearson correlation was observed between infusion pressure and percent of angiographic stenosis (r = .60, P = .0002). All three pressure tests were significantly correlated to the percent stenosis identified after angioplasty. CONCLUSIONS: Pressure measured in the graft during the saline infusion test at a standard rate that simulates optimal graft flow correlates with the angiographic degree of stenosis and warrants further investigation as a useful adjunct to the assessment of revascularization results.
G M Werdick; J R Kruse; A H Cragg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  11     ISSN:  1051-0443     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-04-05     Completed Date:  2000-04-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  171-5     Citation Subset:  IM    
Department of Radiology, University of Minnesota School of Medicine, Minneapolis 55455, USA.
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MeSH Terms
Arteriovenous Shunt, Surgical
Blood Vessel Prosthesis*
Graft Occlusion, Vascular / diagnosis*
Infusions, Intravenous
Renal Dialysis*
Sodium Chloride / diagnostic use*
Reg. No./Substance:
7647-14-5/Sodium Chloride; 9002-84-0/Polytetrafluoroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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