Document Detail

New developments in topical estrogen therapy.
MedLine Citation:
PMID:  8986674     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To review new developments in transdermal E2 therapy in postmenopausal women. DESIGN: A bibliographic search (Medline) of the medical literature from 1966 through 1995 was used to identify new studies evaluating transdermal E2. PATIENT(S): Menopausal and postmenopausal women. RESULT(S): Like oral estrogen, transdermal E2 relieves menopausal symptoms, reverses urogenital atrophy, and conserves bone economy. Initial studies have demonstrated beneficial effects of transdermal E2 on cardiovascular function. Quality of life, patient satisfaction, and compliance also improve with transdermal E2. Advances in transdermal delivery continue to emerge, including low-dose systems and patches that maintain serum E2 levels for a full 7-day period. CONCLUSION(S): New developments in transdermal administration have the potential to increase the number of postmenopausal women who accept and are compliant with long-term estrogen replacement therapy.
R Jewelewicz
Related Documents :
11703894 - Clinical correlates of estrogen replacement therapy use and duration of use among medic...
21365004 - Filaggrin gene defects are independent risk factors for atopic asthma in a polish popul...
9229184 - Effect of estrogens on bone and other systems and hormonal substitute treatment.
16365614 - Impact of hormone therapy on false-positive recall and costs among women undergoing scr...
19863464 - Chronic renal insufficiency, cardiovascular disease and mortality in women: a causal re...
12942554 - Widening disparity in survival between white and african-american patients with breast ...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Fertility and sterility     Volume:  67     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1997 Jan 
Date Detail:
Created Date:  1997-01-23     Completed Date:  1997-01-23     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-12     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Maimonides Medical Center, State University of New York Health Science Center at Brooklyn 11219, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Administration, Cutaneous
Coronary Disease / prevention & control
Estradiol / administration & dosage*,  adverse effects,  pharmacokinetics
Estrogen Replacement Therapy*
Osteoporosis / drug therapy,  prevention & control
Patient Compliance
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Excursion and strain of the median nerve.
Next Document:  Fertility outcome after laparoscopic microsurgical tubal anastomosis.