Document Detail

New developments in mycobacteria identification: public health laboratory modernization.
MedLine Citation:
PMID:  1453097     Owner:  NLM     Status:  MEDLINE    
Clinical laboratory mycobacteriology has traditionally involved long delays for results, primarily due to the slow growth rate of most members of the genus Mycobacterium. Several new methodologies are now available that enable dramatic reductions in turn-around times. These methodologies include the Bactec TB System for isolation and drug susceptibility testing of Mycobacterium tuberculosis, the use of DNA probes, and high performance liquid chromatography (HPLC) for the identification of mycobacterial isolates. The spread of multidrug-resistant tuberculosis has made it imperative that laboratories take advantage of these new methodologies whenever possible. The Mycobacteriology Unit of the Louisiana Office of Public Health's Division of Laboratories has pioneered the use of these methodologies in a public health laboratory setting. Great reductions in turn-around times have been achieved and further reductions are expected as the methods are refined and adapted to the needs of a high-volume public health laboratory.
W G Dupree; H B Bradford
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society     Volume:  144     ISSN:  0024-6921     ISO Abbreviation:  J La State Med Soc     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1993-01-06     Completed Date:  1993-01-06     Revised Date:  2001-03-23    
Medline Journal Info:
Nlm Unique ID:  7505618     Medline TA:  J La State Med Soc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  379-82     Citation Subset:  IM    
Division of Laboratories, Louisiana Dept of Health and Hospitals, New Orleans.
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MeSH Terms
Bacterial Typing Techniques
Chromatography, High Pressure Liquid
DNA Probes
Mycobacterium tuberculosis / classification,  immunology,  isolation & purification*
Tuberculosis, Pulmonary / microbiology*
Reg. No./Substance:
0/DNA Probes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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