Document Detail


New definition of small for gestational age based on fetal growth potential.
MedLine Citation:
PMID:  16612109     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Accurate definition of small for gestational age (SGA) is essential for antenatal as well as postnatal care. SGA is associated with significant antenatal and postnatal pathology. The term, however, includes constitutional smallness, and it is essential to adjust for physiological variation in order to identify those babies who are pathologically small. Maternal height, weight, parity, ethnic origin and the baby's gender have all been found to be significantly associated with normal variation in birth weight. These variables need to be adjusted for to calculate the true growth potential, which can be represented as individually customized fetal growth curves and birth weight percentiles (www.gestation.net). This method for calculating growth potential has been validated in a number of international studies. 'Customized SGA' defines neonates with intrauterine growth restriction, while 'small-normal' does not represent increased risk. Currently, coefficients are being developed for more ethnic groups, to broaden the international applicability of individualized standards. Work is also underway to incorporate the customized birth weight percentile as the starting point of infant growth curves.
Authors:
J Gardosi
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-04-10
Journal Detail:
Title:  Hormone research     Volume:  65 Suppl 3     ISSN:  0301-0163     ISO Abbreviation:  Horm. Res.     Publication Date:  2006  
Date Detail:
Created Date:  2006-04-13     Completed Date:  2006-06-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0366126     Medline TA:  Horm Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  15-8     Citation Subset:  IM    
Copyright Information:
Copyright 2006 S. Karger AG, Basel.
Affiliation:
West Midlands Perinatal Institute, Birmingham, UK. Jason.Gardosi@perinatal.nhs.uk
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MeSH Terms
Descriptor/Qualifier:
Birth Weight / physiology*
Female
Fetal Development / physiology*
Fetal Weight / physiology
Genetic Variation
Humans
Infant, Newborn
Infant, Small for Gestational Age*
Models, Biological*
Pregnancy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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