| New definition of small for gestational age based on fetal growth potential. | |
| | |
MedLine Citation:
|
PMID: 16612109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Accurate definition of small for gestational age (SGA) is essential for antenatal as well as postnatal care. SGA is associated with significant antenatal and postnatal pathology. The term, however, includes constitutional smallness, and it is essential to adjust for physiological variation in order to identify those babies who are pathologically small. Maternal height, weight, parity, ethnic origin and the baby's gender have all been found to be significantly associated with normal variation in birth weight. These variables need to be adjusted for to calculate the true growth potential, which can be represented as individually customized fetal growth curves and birth weight percentiles (www.gestation.net). This method for calculating growth potential has been validated in a number of international studies. 'Customized SGA' defines neonates with intrauterine growth restriction, while 'small-normal' does not represent increased risk. Currently, coefficients are being developed for more ethnic groups, to broaden the international applicability of individualized standards. Work is also underway to incorporate the customized birth weight percentile as the starting point of infant growth curves. |
| | |
Authors:
|
J Gardosi |
Related Documents
:
|
19996479 - Adverse effects of nutritional programming during prenatal and early postnatal life, so... 11430719 - Nitric oxide production during the early neonatal period in small-for-gestational-age i... 6866569 - Sonographic evaluation of the normal ureteral submucosal tunnel in infancy and childhood. 20470449 - Vascular endothelial growth factor and its soluble receptor in infants with congenital ... 18279209 - Extrauterine growth restriction in preterm infants of gestational age < or =32 weeks. 6499719 - Early pregnancy screening for intrauterine growth retardation. 2931509 - Respiratory insufficiency in newborns with abdominal wall defects. 23177799 - Risk assessment in neonatal early onset sepsis. 2407199 - Neurodevelopmental outcome of transient neonatal intracerebral echodensities. |
Publication Detail:
|
Type: Journal Article; Review Date: 2006-04-10 |
Journal Detail:
|
Title: Hormone research Volume: 65 Suppl 3 ISSN: 0301-0163 ISO Abbreviation: Horm. Res. Publication Date: 2006 |
Date Detail:
|
Created Date: 2006-04-13 Completed Date: 2006-06-16 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0366126 Medline TA: Horm Res Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 15-8 Citation Subset: IM |
Copyright Information:
|
Copyright 2006 S. Karger AG, Basel. |
Affiliation:
|
West Midlands Perinatal Institute, Birmingham, UK. Jason.Gardosi@perinatal.nhs.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Birth Weight
/
physiology* Female Fetal Development / physiology* Fetal Weight / physiology Genetic Variation Humans Infant, Newborn Infant, Small for Gestational Age* Models, Biological* Pregnancy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The consequences of being born small - an adaptive perspective.
Next Document: Normal and abnormal fetal growth.