| New cylindrical peptide assemblies defined by extended parallel β-sheets. | |
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MedLine Citation:
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PMID: 23044851 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A new approach to non-covalent peptide-based nanotubular or rod-like structures is presented, whereby the monomeric units are preorganised into a β-strand geometry that templates the formation of an extended and unusual parallel β-sheet rod-like structure. The conformational constraint is introduced by Huisgen cycloaddition to give a triazole-based macrocycle, with the resulting self-assembled structures stabilized by a well-defined series of intermolecular hydrogen bonds. |
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Authors:
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Ashok D Pehere; Christopher J Sumby; Andrew D Abell |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-9 |
Journal Detail:
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Title: Organic & biomolecular chemistry Volume: - ISSN: 1477-0539 ISO Abbreviation: Org. Biomol. Chem. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101154995 Medline TA: Org Biomol Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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School of Chemistry and Physics, The University of Adelaide, North Terrace, Adelaide SA 5005, Australia. andrew.abell@adelaide.edu.au. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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