Document Detail


New considerations in the cause of spontaneous cerebrospinal fluid otorrhea.
MedLine Citation:
PMID:  20684056     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To examine the demographic and radiographic features of patients with spontaneous cerebrospinal fluid otorrhea and to determine whether they display similar characteristics to patients with idiopathic intracranial hypertension. STUDY DESIGN: Retrospective case review. SETTING: Academic, tertiary referral center. PATIENTS: All individuals presenting with spontaneous cerebrospinal fluid otorrhea, diagnosed between 2000 and 2009, undergoing primary surgical repair. INTERVENTIONS: All patients underwent surgical repair via a transmastoid, middle fossa, or combined transmastoid-middle fossa approach. MAIN OUTCOME MEASURES: Patient demographics such as age, race, sex, height, weight, and body mass index, the presence of a radiographically empty or partially empty sella, and preoperative radiographic and intraoperative surgical findings of the temporal bone. RESULTS: Twenty-three patients underwent primary surgical repair for spontaneous cerebrospinal fluid otorrhea. Fifteen patients underwent preoperative magnetic resonance imaging of the head with 12 (80%) demonstrating the presence of an empty or partially empty sella. Mean body mass index of those patients with an empty or partially empty sella was 38.0 kg/m2 compared with 28.5 kg/m2 for those without an empty sella. CONCLUSION: Patients with spontaneous cerebrospinal fluid otorrhea are often middle-aged and obese, with females being affected nearly twice as often as males. Empty or partially empty sella was observed in 80% of patients with spontaneous cerebrospinal fluid otorrhea as demonstrated by preoperative magnetic resonance imaging. Patients with spontaneous cerebrospinal fluid otorrhea who display these demographic and radiographic features should be further evaluated for the presence of idiopathic intracranial hypertension.
Authors:
John C Goddard; Ted Meyer; Shaun Nguyen; Paul R Lambert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology     Volume:  31     ISSN:  1537-4505     ISO Abbreviation:  Otol. Neurotol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-03     Completed Date:  2010-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100961504     Medline TA:  Otol Neurotol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  940-5     Citation Subset:  IM    
Affiliation:
Medical University of South Carolina, Department of Otolaryngology-Head and Neck Surgery, Charleston, South Carolina, USA. jgoddard@hei.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cerebrospinal Fluid Otorrhea / epidemiology,  etiology*,  radiography
Cranial Fossa, Middle / surgery
Empty Sella Syndrome / complications
Encephalocele / complications,  surgery
Female
Humans
Magnetic Resonance Imaging
Male
Meningocele / complications,  surgery
Middle Aged
Otologic Surgical Procedures
Pseudotumor Cerebri / complications,  epidemiology
Retrospective Studies
Temporal Bone / abnormalities,  pathology
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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