Document Detail


New conclusive data on human myocardial dysfunction induced by acidosis.
MedLine Citation:
PMID:  23134672     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
ABSTRACT: Acidosis is one of the major consequences of hemodynamic instability in shock state patients directly associated with multiple organ failure evolution and death. Most studies on the hemodynamic consequences of acidosis have been experimental, nonhuman studies with severe acidosis, and thus far from the most common clinical situations. Schotola and colleagues offer a new approach to human failing myocardium where the authors highlight, ex vivo, the deleterious hemodynamic consequences of mild acidosis. Their work strengthens the current view of the urgent need to discover new efficient and nondeleterious therapy for the treatment of acidosis.
Authors:
Antoine Kimmoun; Nicolas Ducrocq; Bruno Levy
Publication Detail:
Type:  EDITORIAL     Date:  2012-9-28
Journal Detail:
Title:  Critical care (London, England)     Volume:  16     ISSN:  1466-609X     ISO Abbreviation:  Crit Care     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-11-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9801902     Medline TA:  Crit Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  160     Citation Subset:  -    
Affiliation:
INSERM, Groupe Choc, contrat Avenir INSERM, U961, Faculté de Médecine, 54511 Vandoeuvre les Nancy, France. blevy@sfr.fr.
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