| New cassane diterpenes from Caesalpinia echinata. | |
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MedLine Citation:
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PMID: 21641971 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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An investigation of the ethanolic extract from stems of Caesalpinia echinata Lam (Leguminosae-Caesalpinioideae) led to the isolation of five new cassane diterpenes along with known lambertianic acid. Their structures were determined based on spectroscopic methods. A preliminary study on leishmanicidal activity demonstrated that compounds 1, 2 and 6 were found to inhibit the growth of amastigote-like forms of Leishmania amazonensis without affecting mononuclear cells obtained from human peripheral blood. |
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Authors:
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Betania Barros Cota; Djalma Menezes de Oliveira; Ezequias Pessoa de Siqueira; Elaine Maria Souza-Fagundes; Adriano M C Pimenta; Daniel M Santos; Ana Rabello; Carlos Leomar Zani |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-27 |
Journal Detail:
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Title: Fitoterapia Volume: - ISSN: 1873-6971 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-6-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 16930290R Medline TA: Fitoterapia Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier B.V. |
Affiliation:
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Laboratório de Química de Produtos Naturais, Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Av. Augusto de Lima, 1715, Belo Horizonte, MG, 30190-002, Brazil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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